how to replace {} words in long rich text in c#

how to replace {} words in long rich text in c# easily

For example

Dear User,

{Title} - {Description} for {CustomerName} has been Appproved by all Approvers. 

Now I want to get all {} inside words(these are internal sp list column names and replace it with actual sharepoint list item value.

MCTS Sharepoint 2010, MCAD dotnet, MCPDEA, SharePoint Lead